Best Sales Cadence Tools for Sequence Automation in 2026

We tested 15+ sales cadence platforms to find the best for building automated sequences. These tools help you create multi-touch campaigns across email, phone, LinkedIn, and other channels without manual follow-up tracking.

Last updated: January 23, 2026Reviewed 15+ tools

Sales cadence tools showing sequence automation

Feature Comparison

ToolStarting PriceChannelsAI FeaturesBuilt-in DialerBest ForOur Rating
OutreachCustomAllAdvancedEnterprise9.5/10
SalesloftCustomAllAdvancedEnterprise9.3/10
Apollo.ioFreeEmail + PhoneGoodSMB9.2/10
Reply.io$60/user/moEmail + LinkedInGoodSMB8.9/10
Lemlist$39/moEmail + LinkedInBasicSMB8.7/10
Instantly$37/moEmail onlyBasicSMB8.6/10
Mailshake$58/user/moEmail + PhoneBasicSMB8.4/10

Deep Dives

1

Outreach

Best Overall
Outreach sequence builder and analytics

Outreach is the enterprise leader in sales engagement. Beyond sequences, it offers revenue intelligence, conversation analytics, and deal insights. The sequence builder is the most flexible available, with branching logic and AI optimization.

Starting priceCustom

Strengths

  • Most powerful sequence builder
  • Full revenue intelligence
  • AI-powered insights
  • Enterprise integrations
  • Excellent support

Limitations

  • Enterprise pricing
  • Complex implementation
  • Overkill for small teams
  • Long sales cycle to buy
Who it's for: Best for enterprise sales teams with dedicated sales ops and budget.
Try Outreach
2

Salesloft

Best for Teams
Salesloft cadence and coaching features

Salesloft combines powerful cadences with conversation intelligence and coaching features. The platform helps reps execute sequences while managers coach and analyze performance.

Starting priceCustom

Strengths

  • Excellent cadence builder
  • Conversation intelligence
  • Coaching features
  • Strong analytics
  • Good integrations

Limitations

  • Enterprise pricing
  • Similar cost to Outreach
  • Implementation required
  • Learning curve
Who it's for: Best for mid-market and enterprise teams focused on coaching and improvement.
Try Salesloft
3

Apollo.io

Best for Beginners
Apollo.io data and sequence platform

Apollo combines a massive contact database with sequence automation. Find leads and enroll them in sequences without switching tools. The free tier is genuinely useful for getting started.

Starting priceFree

Strengths

  • Data + sequences combined
  • Generous free tier
  • Affordable paid plans
  • Good dialer
  • Easy to learn

Limitations

  • Data quality varies
  • Less enterprise features
  • Simpler sequence logic
  • Fewer integrations
Who it's for: Best for SMBs who want prospecting data and sequences in one affordable tool.
Try Apollo
4

Reply.io

Reply.io multi-channel sequences

Reply.io offers strong multi-channel sequences with AI personalization. The platform handles email, LinkedIn, and calls with built-in warm-up and deliverability features.

Starting price$60/user/mo

Strengths

  • Strong multi-channel
  • AI personalization
  • Built-in warm-up
  • LinkedIn automation
  • Cloud dialer

Limitations

  • Per-user pricing adds up
  • LinkedIn limits apply
  • Interface can be busy
  • Support response times
Who it's for: Best for teams doing true multi-channel outreach across email and LinkedIn.
Try Reply.io
5

Lemlist

Lemlist personalization and sequences

Lemlist differentiates with creative personalization features. Add personalized images and videos to emails automatically. Lemwarm included helps deliverability.

Starting price$39/mo

Strengths

  • Unique image personalization
  • Video in email
  • Lemwarm included
  • Good templates
  • Active community

Limitations

  • No built-in dialer
  • Simpler sequence logic
  • Limited team features
  • Can feel gimmicky
Who it's for: Best for creative outreach that stands out with visual personalization.
Try Lemlist
6

Instantly

Best for Budget
Instantly unlimited email accounts

Instantly focuses on high-volume cold email with unlimited sending accounts. AI-powered warm-up helps deliverability across all accounts. Great for agencies and high-volume senders.

Starting price$37/mo

Strengths

  • Unlimited email accounts
  • AI warm-up included
  • Lead finder built-in
  • Very affordable
  • Simple interface

Limitations

  • Email only
  • No phone or LinkedIn
  • Less team features
  • Simpler analytics
Who it's for: Best for high-volume cold emailers and agencies running multiple accounts.
Try Instantly
7

Mailshake

Mailshake simple sequence builder

Mailshake offers simple, effective sequences without overwhelming features. The dialer is included, LinkedIn steps work well, and the interface is clean and easy to learn.

Starting price$58/user/mo

Strengths

  • Easy to learn
  • Dialer included
  • LinkedIn tasks
  • Good support
  • Clean interface

Limitations

  • Less advanced features
  • Per-user pricing
  • Limited automation
  • Basic reporting
Who it's for: Best for teams who want simple sequences without enterprise complexity.
Try Mailshake

How We Evaluated

We tested each platform for sequence building, automation, and team workflows.

  • Sequence Building (30%)Flexibility and ease of creating multi-touch cadences.
  • Channel Coverage (25%)Email, phone, LinkedIn, and other channel support.
  • Automation (20%)Smart automation, triggers, and AI features.
  • Analytics (15%)Sequence performance tracking and optimization.
  • Pricing (10%)Value for teams at different sizes.

How to Choose

  • Choose Outreach if you need enterprise sales team.
  • Choose Salesloft if you need coaching and improvement.
  • Choose Apollo.io if you need data + sequences combined.
  • Choose Instantly if you need high-volume cold email.
  • Choose Lemlist if you need creative personalization.

Common Questions

Good cadences are multi-touch (5-8 touches minimum), multi-channel (email + phone + LinkedIn), spaced appropriately (not too aggressive), and personalized at least at the opening line. Test different cadence lengths and spacing for your audience.

Research suggests 8-12 touches over 3-4 weeks for cold outreach. Most responses come after touch 4-7. Too few touches and you leave deals on the table; too many and you risk reputation damage.

No. Create different cadences for different personas, industries, or intent levels. A cold prospect needs a different approach than someone who downloaded your whitepaper. Segment your cadences by use case.